Dr. Francesco Manoli

ISOF  -  CNR Via Gobetti, 101 40129 Bologna (Italy) Phone: +39 051 639 9814 Fax:      +39 051 639 9844 E-mail: francesco.manoli @isof.cnr.it

Born in Monselice (Padua), January 17, 1960
Married, two children

Studies:
1979. Secondary school diploma in Industrial Chemistry at Istituto Tecnico Industriale Statale "G. Natta" of Padua
1991. Graduate Degree in Pharmacy at "Università degli Studi di Padova" discussing the thesis "Phenylpentadiene tricarbonylchromium complexes: synthesis and structure"

Work:
October 1979 - October 1982: Representative of reagents and equipments for laboratory
October 1982 - December 1986: Technical assistant at Istituto Tecnico Industriale Statale "G. Natta" of Padua in the analytical chemistry and biological chemistry laboratories
On January 1^st 1987 Dr. Francesco Manoli obtained a permanent position as technician at "Centro di Studi sugli Stati Molecolari Radicalici ed Eccitati", National Research Council - C.N.R. of Padua.
Here he organized the laboratory of organometallic synthesis and prepared several new organometallic complexes of aromatic compounds activated by transition metals (Cr, Rh, Ir and Pt) using synthetic techniques under inert atmosphere; complexes were purified with chromatographique techniques and characterized with GLC, HPLC, FT-IR, UV-Vis, NMR techniques. This type of complexes have applications in catalytic processes and offer interesting perspectives in pharmacology.
In August 2000, he moved to "Istituto per la Sintesi Organica e la Fotoreattività" (ISOF), C.N.R. of Bologna.
Here Dr. Manoli has gained confidence in spectroscopic methods like UV-Vis absorption spectroscopy, circular dichroism, steady state and time-resolved luminescence spectroscopy. These methods are applied to the study of the interaction between drugs and model receptors, like cyclodextrins and carrier proteins.